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RECRUITING
Updated: Oct 31, 2024

Observational Study to Observe Variations of Gait Parameters in Patients with Neuromuscular Diseases

Brief Summary

This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases. Furthermore, the investigators want to evaluate the feasibility of collecting physical activity in daily life conditions during a one-week monitoring period using a wearable sensor.

Key Information

Inclusion Criteria:

  • Ambulant adult patients with genetic diagnosis of muscular dystrophy/myopathy (dystrophinopathies, muscular dystrophies and congenital and non-congenital myopathies), of spinal muscular atrophy (SMA) and with molecular diagnosis of Charcot-Marie Tooth 1 or 2.
  • independent walking, even with assistance;

Exclusion Criteria:

  • Dilated or ischemic heart disease with moderate impairment;
  • Chronic respiratory failure: forced vital capacity (FVC) < 40%; more than 5% of nocturnal time spent with peripheral oxygen saturation levels < 90.

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